There is a life threatening negative dating anywhere between c and you may ? playing with independent (non-overlapping) 100-kb windows: Spearman’s Roentgen = ?0

There is a life threatening negative dating anywhere between c and you may ? playing with independent (non-overlapping) 100-kb windows: Spearman’s Roentgen = ?0

We in addition to observe a terrible relationship ranging from total ? and you may ? [R = ?0

c and you can ? according to a hundred-kb surrounding window which have screen classified on the 6 categories of equal count centered on c [CO1, Co2, . CO6 proving increasing cost regarding c] The average c (cM/Mb/female meiosis) values towards six groups are: 0.078 (CO1), 0.727 (CO2), step one.439 (CO3), dos.294 (CO4), step three.299 (CO5) and you may 5.964 (CO6). Blue articles work when whole chromosomes is analyzed. Lime columns work once deleting centromeric and telomeric regions with significantly quicker CO rates. 1246 (P = step 1.6?10 ?5 ) to have whole chromosomes and you will R = ?0.1191 (P = step one.2?10 ?4 ) once deleting telomeric/centromeric places.

Multiple hypotheses can be put toward explain the other landscapes to own CO and GC over the D. melanogaster genome. Divergent DSB repair paths had been suggested when you look at the Drosophila such as fungus , , which have a synthesis-built strand annealing sugar baby Austin TX (SDSA) pathway which is related just with GC situations, because the solution of your double Holliday junction (DHJ) is make both CO or GC (Contour S1). (mehr …)

WeiterlesenThere is a life threatening negative dating anywhere between c and you may ? playing with independent (non-overlapping) 100-kb windows: Spearman’s Roentgen = ?0